Weight loss medications have revolutionised how people manage obesity. However, one of the things that often gets overlooked is that dehydration is a common side effect of weight-loss drugs, such as Mounjaro (tirzepatide) and Wegovy (semaglutide). These work by altering your hormones that control appetite and sugar levels.
If you are currently taking or considering weight loss medications, it is important to stay hydrated on weight loss medications. In this blog, we will explore why hydration matters for weight loss drugs, how much water you should be drinking, and smart tips to support your weight loss journey.
Why hydration is crucial while taking weight loss medications?
As weight loss injections work by altering natural hormones, they affect the function of the digestive system and kidneys. A randomised control trial found that GLP-1 receptor agonists reduce fluid intake, indicating a direct influence on the hydration status in individuals.
Here’s why hydration matters while on weight loss drugs:
Reduces common side effects
Weight loss injection side effects include headache, nausea, constipation, and fatigue. These are frequent complaints among users and can worsen with dehydration.
Improves metabolism
A well-hydrated body burns fat more effectively.
Prevents kidney strain
Reduced calorie and fluid intake puts a strain on the kidneys, and a balanced water intake makes them work efficiently.
Supports digestion
While on weight loss drugs, gastric emptying is slowed down. Water helps in moving the food faster through the system.
How much water should you drink?
It is essential to stay hydrated on weight loss medications. A common guideline for people on weight loss injections is:
- 35-40 ml per kg of body weight daily
- If you weigh 70 kg, you should aim for 2.5 to 2.8 litres per day. This includes water from drinks and foods like fruits and soups.
- If you are physically active, spending time in hot environments, or dealing with constipation, you may need more water.
Mounjaro and hydration
Mounjaro (tirzepatide) has a dual action on GLP-1 and GIP receptors. While effective for weight loss and blood sugar control, it often causes common side effects like nausea, vomiting, headache and dry mouth, especially in the early weeks of weight loss treatment.
Here is how hydration helps on Mounjaro:
- Ease gastrointestinal discomfort
- Reduce dizziness or fatigue
- Replace lost fluids from vomiting or diarrhoea
Drinking water on Wegovy
Wegovy (semaglutide) slows digestion and reduces your appetite, and it may go unnoticed but it sometimes leads to lower fluid intake.
Here’s how hydration helps on Wegovy:
- Prevents constipation
- Reduces headaches
- Prevents tiredness
In the STEP 8 trial, gastrointestinal side effects, including nausea and constipation, were common among users, highlighting the importance of hydration.
Hydration tips for weight loss medication users
If you are finding it hard to drink enough water frequently while being on weight loss drugs. Here are some practical and effective hydration tips:
1. Start your day with water
Drink a glass of water first thing in the morning to kick-start your metabolism and flush out overnight toxins.
2. Sip throughout the day
Large gulps can cause nausea and bloating, especially if you’re on weight loss medications. Try sipping small amounts throughout the day to stay hydrated.
3. Carry a water bottle
Carrying a reusable water bottle is a visual reminder to drink water throughout the day.
4. Use a hydration app
Set reminders or use a hydration app to stay consistent, especially during busy days.
5. Eat water-rich foods
Include water-rich foods in your diet, such as cucumber, celery, watermelon, and oranges. Most of them are over 90% water and contribute to your daily hydration needs.
6. Flavour it naturally
If plain water doesn’t appeal to you, infuse it with lemon, cucumber and berries without added sugar.
Can electrolytes or supplements help?
While you’re losing weight, you may experience symptoms of electrolyte imbalance, such as dizziness, muscle cramps, or fatigue. Here is what helps:
Electrolyte tablets or drinks
Look for sugar-free options with sodium, potassium and magnesium, this also helps in relieving constipation
Coconut water
It is a natural source of potassium, essential for muscle and nerve function
Oral rehydration salts (ORS)
If experiencing vomiting or diarrhoea, ORS may be useful
Choose sugar-free options when selecting electrolyte tablets, and always consult a healthcare provider before starting new supplements.
Best drinks while losing weight
While water should be your primary drink to stay hydrated on weight loss medications, here are other smart options:
Herbal teas
Peppermint, ginger, and chamomile teas support digestion and hydration without caffeine consumption.
Electrolyte drinks
If you’re sweating a lot during workouts or experiencing headaches, a low-calorie or sugar-free electrolyte drink can help replenish lost minerals.
Drinks you should avoid
- Sugary sodas
- High-calorie smoothies
- Alcohol
Final thoughts
If you’re taking medications like Wegovy, Ozempic, or Mounjaro, staying hydrated is crucial. Batley Pharmacy offers pharmacist-supervised weight loss injections, Mounjaro and Wegovy. These are available only if you meet the eligibility criteria. Our team will assess your suitability and provide guidance every step of the way, including how to stay hydrated for the best results.
